RPPanalyzer: Analysis of reverse-phase protein array data
نویسندگان
چکیده
SUMMARY RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data. Implemented plotting functions permit a quality control by monitoring data distribution and signal validity. Finally, the data can be visualized in heatmaps, boxplots, time course plots and correlation plots. RPPanalyzer is a flexible tool and tolerates a huge variety of different experimental designs. AVAILABILITY The RPPAanalyzer is open source and freely available as an R-Package on the CRAN platform http://cran.r-project.org/.
منابع مشابه
RPPanalyzer toolbox: an improved R package for analysis of reverse phase protein array data.
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (RPPA) data. The R package RPPanalyzer was designed for data preprocessing followed by basic statistical analyses and proteomic data visualization. ...
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ورودعنوان ژورنال:
- Bioinformatics
دوره 26 17 شماره
صفحات -
تاریخ انتشار 2010